Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9225483 | 0.99 | MEN1 (0.57) | MEN1KMT2AGAARAB9ASLC40A1 | |
| SCHEMBL14267565 | 0.95 | MEN1 (0.56) | MEN1KMT2AGAARAB9ASLC40A1 | |
| Hydrochloric Acid SCHEMBL9222575 | 0.93 | MEN1 (0.54) | MEN1KMT2AGAARAB9ASLC40A1 | |
| Hydrochloric Acid SCHEMBL9228360 | 0.90 | MEN1 (0.59) | MEN1KMT2AGAARAB9ASLC40A1 | |
| SCHEMBL9220315 | 0.84 | RXFP1 (0.57) | GAANAMPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9229016 | 0.83 | RXFP1 (0.56) | GAANAMPTALDH1A1 | |
| SCHEMBL9225001 | 0.83 | MEN1 (0.59) | MEN1KMT2AGAARAB9ASLC40A1 | |
| Hydrochloric Acid SCHEMBL9220254 | 0.82 | GAA (0.58) | MEN1KMT2AGAARAB9ASLC40A1 | |
| SCHEMBL9228930 | 0.81 | MEN1 (0.55) | MEN1KMT2AGAARAB9ASLC40A1 | |
| SCHEMBL9226850 | 0.81 | KDM4E (0.61) | MEN1KMT2AGAARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | claimed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | claimed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |