Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227892 | 0.89 | RAB9A (0.51) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| SCHEMBL9228612 | 0.82 | KMT2A (0.55) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9228293 | 0.81 | MEN1 (0.58) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9225483 | 0.80 | MEN1 (0.57) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9228689 | 0.80 | ALDH1A1 (0.51) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| SCHEMBL28654832 | 0.77 | PTGS2 (0.71) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| SCHEMBL14267565 | 0.76 | MEN1 (0.56) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| SCHEMBL23200324 | 0.74 | KDM4E (0.78) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| SCHEMBL31061034 | 0.74 | KDM4E (0.78) | KDM4EHSD17B10GAAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9222575 | 0.74 | MEN1 (0.54) | KDM4EHSD17B10GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |