Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 1.00 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | EEF2K | O00418 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228323 | 1.00 | GABBR2 (1.00) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL27718747 | 0.98 | GABBR2 (0.96) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL1821479 | 0.83 | PTGS1 (0.74) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL1821480 | 0.83 | PTGS1 (0.74) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL29153370 | 0.80 | GABBR2 (0.67) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL29153372 | 0.80 | GABBR2 (0.67) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL85764 | 0.79 | GABBR2 (0.66) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| Water SCHEMBL1502206 | 0.78 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| Water SCHEMBL1502204 | 0.78 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL20629917 | 0.78 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | disclosed |