Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.67 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.67 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.67 |
| ▸ | CDK1 | P06493 | 2/20 | 0.67 |
| ▸ | CDK2 | P24941 | 2/20 | 0.67 |
| ▸ | LTK | P29376 | 2/20 | 0.67 |
| ▸ | CDK8 | P49336 | 2/20 | 0.67 |
| ▸ | PRKX | P51817 | 2/20 | 0.67 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.67 |
| ▸ | STK3 | Q13188 | 2/20 | 0.67 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.67 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.67 |
| ▸ | CHUK | O15111 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682220 | 1.00 | ROCK2 (0.67) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL987765 | 0.91 | ROCK2 (0.67) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL9234272 | 0.89 | ROCK2 (0.66) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL9234264 | 0.89 | ROCK2 (0.66) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL9234373 | 0.87 | ROCK2 (0.63) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL6684026 | 0.87 | ROCK2 (0.63) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL9232366 | 0.87 | ROCK2 (0.63) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL987766 | 0.87 | ROCK2 (0.63) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL6689278 | 0.87 | ROCK2 (0.63) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL9234442 | 0.86 | ROCK2 (0.62) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641781-A1 | 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | claimed |
| US-5478838-A | Treating hypertension, angina pectoris, asthma, improving peripheral circulation | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0641781-A1 | 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |