SCHEMBL9228497

SCHEMBL9228497

C=CC(=O)OC(CC)COC(=O)CCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 6/20 0.35
▸ MAOB P27338 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MAOA P21397 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ACHE P22303 1/20 0.33
▸ HTT P42858 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ AGTR1 P30556 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ NPC1 O15118 2/20 0.31
▸ RAB9A P51151 2/20 0.31
▸ PKM P14618 1/20 0.31
▸ ALOX5 P09917 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9228170 0.91 MAOB (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10471728 0.91 ALDH1A1 (0.37) GAAMAOBKMT2AMAOAMEN1
SCHEMBL9227024 0.90 GAA (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10470440 0.88 MAOB (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL9230983 0.87 GAA (0.35) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10395151 0.87 GAA (0.35) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10472259 0.84 GAA (0.37) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10395582 0.84 GAA (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10470534 0.84 GAA (0.38) GAAMAOBKMT2AMAOAMEN1
SCHEMBL9871543 0.83 GAA (0.39) GAAMAOBKMT2AMAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476882-A Containing 2,2,6,6-tetraalkylpiperidine derivative CIBA-GEIGY CORPORATION (US) 1995-12-19 — — US disclosed
US-5274016-A Crosslinked polyolefin core and stabilizer of a 2,2,6,6-tetramethylpiperidine derivative having at least one ethylenic double bone CIBA-GEIGY CORPORATION (US) 1993-12-28 — — US disclosed
EP-0296391-B1 LIGHT-STABILIZED POLYMER MICROPARTICLES CONTAINING EPOXY GROUPS CIBA-GEIGY AG (CH) 1993-07-07 — — EP disclosed
EP-0226538-B1 LIGHT STABILIZED POLYMER MICROPARTICLES Ciba SC Holding AG (CH) 1991-09-11 — — EP disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 — — US disclosed
US-4892915-A Copolymers of 2-(2-hydroxy-5-acryloyloxyalkyl)phenyl-2H-benzotriazoles CIBA-GEIGY CORPORATION (US) 1990-01-09 — — US disclosed
EP-0296391-A2 Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY AG (CH) 1988-12-28 — — EP disclosed
EP-0133164-B1 COMPOUNDS WHICH CAN BE COPOLYMERISED CIBA-GEIGY AG (CH) 1988-12-14 — — EP disclosed
US-4785063-A LIGHT STABILIZERS CIBA-GEIGY CORPORATION (US) 1988-11-15 — — US disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 — — EP disclosed
EP-0133164-A2 Compounds which can be copolymerised CIBA-GEIGY AG (CH) 1985-02-13 — — EP disclosed
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