SCHEMBL9229017

SCHEMBL9229017

COc1ccc([Si]([O])(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.58
CA2 P00918 6/20 0.58
CA9 Q16790 3/20 0.58
CA7 P43166 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ACHE P22303 1/20 0.48
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP2A6 P11509 1/20 0.46
PKM P14618 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 2/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2544548 0.78 CA1 (0.65) CA1CA2CA9CA7CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.76 CA1 (1.00) CA1CA2CA9CA7CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.76 CA1 (1.00) CA1CA2CA9CA7CA12
SCHEMBL19862402 0.76 CA1 (0.61) CA1CA2CA9CA7CA12
SCHEMBL275937 0.76 CA1 (0.61) CA1CA2CA9CA7CA12
SCHEMBL28701305 0.76 CA1 (0.61) CA1CA2CA9CA7CA12
SCHEMBL1223789 0.74 CA1 (0.58) CA1CA2CA9CA7CA12
SCHEMBL1225152 0.74 CA1 (0.58) CA1CA2CA9CA7CA12
SCHEMBL9247963 0.74 CA1 (0.58) CA1CA2CA9CA7CA12
SCHEMBL12816764 0.74 CA1 (0.58) CA1CA2CA9CA7CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464959-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1995-12-20 EP claimed
EP-0284370-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-22 EP claimed
EP-0464959-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1995-12-20 EP disclosed
EP-0344891-B1 Tetraazaporphin, process for producing the same, as well as optical recording media using the same and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1994-07-27 EP disclosed
US-5284943-A Containing Si, Ge or Sn HITACHI CHEMICAL COMPANY, CO. (JP) 1994-02-08 US disclosed
US-5217856-A TETRAAZAPORPHIN, PROCESS FOR PRODUCING THE SAME, AS WELL AS OPTICAL RECORDING MEDIA USING THE SAME AND PRODUCTION PROCESSES THEREOF HITACHI CHEMICAL CO., LTD. (JP) 1993-06-08 US disclosed
EP-0344891-A2 Tetraazaporphin, process for producing the same, as well as optical recording media using the same and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1989-12-06 EP disclosed