SCHEMBL9229111

SCHEMBL9229111

CCC(CO)(CO)COCC(C)O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 1/20 0.37
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL505898 0.89 HSD17B10 (0.50) HSD17B10TDP1MAPK1TSHRTHRB
SCHEMBL5904489 0.89 HSD17B10 (0.44) HSD17B10TDP1MAPK1
SCHEMBL20717767 0.89 HSD17B10 (0.44) HSD17B10TDP1MAPK1
SCHEMBL24835632 0.87 HSD17B10 (0.43) HSD17B10TDP1MAPK1
SCHEMBL11278496 0.83 TDP1 (0.49) HSD17B10TDP1MAPK1
SCHEMBL13168203 0.82 HSD17B10 (0.50) HSD17B10TDP1MAPK1TSHR
SCHEMBL11001055 0.82 THRB (0.36) HSD17B10TDP1THRB
SCHEMBL937927 0.82 USP2 (0.44) HSD17B10THRB
SCHEMBL13473660 0.80 HSD17B10 (0.38) HSD17B10TDP1MAPK1
SCHEMBL45482 0.79 THRB (0.36) MAPK1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384183-B1 Mixtures comprising silanol-terminated polydiorganosiloxane and processes GEN ELECTRIC (US) 1995-08-02 EP disclosed
EP-0104179-B1 SCAVENGERS FOR ONE-COMPONENT ALKOXY-FUNCTIONAL RTV COMPOSITIONS AND PROCESSES GENERAL ELECTRIC COMPANY (US) 1991-01-02 EP disclosed
EP-0104179-A4 SCAVENGERS FOR ONE-COMPONENT ALKOXY-FUNCTIONAL RTV COMPOSITIONS AND PROCESSES. GEN ELECTRIC (US) 1984-07-24 EP disclosed
EP-0104179-A1 SCAVENGERS FOR ONE-COMPONENT ALKOXY-FUNCTIONAL RTV COMPOSITIONS AND PROCESSES. GEN ELECTRIC (US) 1984-04-04 EP disclosed
US-4417042-A Scavengers for one-component alkoxy-functional RTV compositions and processes GENERAL ELECTRIC COMPANY (US) 1983-11-22 US disclosed
WO-1983002948-A1 SCAVENGERS FOR ONE-COMPONENT ALKOXY-FUNCTIONAL RTV COMPOSITIONS AND PROCESSES GEN ELECTRIC (US) 1983-09-01 WO disclosed