Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229117 | 0.87 | ALOX5 (0.60) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9228908 | 0.86 | ALOX5 (0.71) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9224490 | 0.83 | ALOX5 (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9226906 | 0.82 | ALOX5 (0.60) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9209059 | 0.81 | ALOX5 (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9218003 | 0.81 | ALOX5 (0.55) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9210578 | 0.80 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9215709 | 0.79 | ALOX5 (0.77) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9226057 | 0.77 | ALOX5 (0.52) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9228832 | 0.77 | ALOX5 (0.54) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375404-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-02-09 | — | — | EP | claimed |
| EP-0375404-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| US-5403859-A | PHENYLENE-CYCLIC ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-04 | — | — | US | disclosed |
| EP-0375404-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-02-09 | — | — | EP | disclosed |
| US-5234950-A | Antiallergens, antiinflammatory agents; cardiovascular disorders, antiarthritic | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| US-5098930-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0375404-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |