Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227260 | 0.85 | ALOX5 (0.53) | ALOX5CA12CA1CA2CA7 | |
| SCHEMBL9224922 | 0.85 | ALOX5 (0.74) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9228908 | 0.83 | ALOX5 (0.71) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9222894 | 0.83 | ALOX5 (0.71) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9228252 | 0.83 | ALOX5 (0.71) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9229199 | 0.83 | ALOX5 (0.71) | ALOX5PTGS1PTGS2CA12CA1 | |
| SCHEMBL9227966 | 0.81 | ALOX5 (0.68) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9222711 | 0.81 | ALOX5 (0.67) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9224569 | 0.80 | ALOX5 (0.48) | ALOX5CA12CA1CA2CA7 | |
| SCHEMBL9229995 | 0.79 | ALOX5 (0.65) | ALOX5PTGS1PTGS2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403859-A | PHENYLENE-CYCLIC ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-04 | — | — | US | disclosed |
| EP-0375404-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-02-09 | — | — | EP | disclosed |
| US-5234950-A | Antiallergens, antiinflammatory agents; cardiovascular disorders, antiarthritic | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| US-5098930-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0375404-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |