Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886282 | 0.77 | TDP1 (0.37) | — | |
| SCHEMBL4387890 | 0.76 | — | — | |
| SCHEMBL27795684 | 0.70 | — | — | |
| Bicarbonate SCHEMBL10697021 | 0.67 | HTT (0.36) | NPC1MAPTMAPK1HTTRAB9A | |
| SCHEMBL1920833 | 0.64 | HTR2A (0.33) | — | |
| SCHEMBL15223866 | 0.64 | MMP1 (0.33) | NPC1MAPTMAPK1HTTRAB9A | |
| SCHEMBL10438765 | 0.63 | NPC1 (0.38) | NPC1MAPTMAPK1HTTRAB9A | |
| SCHEMBL9509496 | 0.61 | CA1 (0.33) | NPC1MAPTMAPK1HTTRAB9A | |
| SCHEMBL18762848 | 0.61 | USP2 (0.35) | — | |
| SCHEMBL21226031 | 0.60 | SLC22A6 (0.36) | NPC1MAPTMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420117-A | Antitumor agents | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0378706-B1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| EP-0378706-A1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1990-07-25 | — | — | EP | disclosed |