SCHEMBL9229263

SCHEMBL9229263

CCOC(=O)c1[nH]c(CN(CC)CC)c(CC)c1CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 2/20 0.41
GAA P10253 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALOX12 P18054 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 3/20 0.41
IGF1R P08069 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HTR6 P50406 2/20 0.39
HTR1A P08908 1/20 0.39
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
HTR1D P28221 1/20 0.39
HTR1B P28222 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11648083 0.84 CYP1A2 (0.55) CYP1A2CYP2C19CYP2C9TSHRGAA
Hydrochloric Acid SCHEMBL10924459 0.76 MAPT (0.49) CYP1A2CYP2D6CYP2C19CYP2C9TSHR
SCHEMBL11647620 0.76 CYP1A2 (0.58) CYP1A2CYP2C19CYP2C9TSHRGAA
SCHEMBL8654844 0.75 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9KMT2ANPSR1
SCHEMBL4201730 0.75 CYP1A2 (0.67) CYP1A2CYP2C19CYP2C9TSHRNPSR1
SCHEMBL5858401 0.74 CYP1A2 (0.55) CYP1A2CYP2C19CYP2C9KMT2ANPSR1
SCHEMBL11648233 0.72 CYP1A2 (0.62) CYP1A2CYP2D6CYP2C19CYP2C9TSHR
SCHEMBL8654140 0.72 CYP1A2 (0.53) CYP1A2CYP2C19CYP2C9KMT2ANPSR1
SCHEMBL11650167 0.72 CYP1A2 (0.53) CYP1A2CYP2D6CYP2C19CYP2C9TSHR
SCHEMBL11649200 0.72 CYP1A2 (0.67) CYP1A2CYP2C19CYP2C9TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5464741-A Palladium (II) octaethylporphine alpha-isothiocyanate as a phosphorescent label for immunoassays HENWELL, INC. (US) 1995-11-07 US disclosed