Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644037 | 0.87 | CYP1A2 (0.76) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL4205954 | 0.87 | CYP1A2 (0.76) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL8654844 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL11648083 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL5858401 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL8204552 | 0.82 | BRD4 (0.62) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL8654140 | 0.81 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL2565795 | 0.80 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL8720089 | 0.80 | RAB9A (0.82) | ALDH1A1MAPK1NPSR1SMN1; SMN2RAB9A | |
| SCHEMBL9423348 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106599-A | Inks | XEROX CORPORATION (US) | 2000-08-22 | — | — | US | claimed |
| WO-2020210761-A1 | BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME | NITTO DENKO CORPORATION (JP) | 2020-10-15 | — | — | WO | disclosed |
| US-7538231-B2 | Tyrosine kinase inhibitors | MERCK & CO, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1651209-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20060276514-A1 | Tyrosine kinase inhibitors | MERCK & CO., INC. | 2006-12-07 | — | — | US | disclosed |
| EP-1651209-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| US-6878786-B2 | Process for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-04-12 | — | — | US | disclosed |
| WO-2005009373-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| US-6841501-B2 | Catalyst system for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-01-11 | — | — | US | disclosed |
| EP-1173445-B1 | ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-20020038036-A1 | \"Catalyst system for the polymerization of olefins\ | EQUISTAR CHEMICALS, LP | 2002-03-28 | — | — | US | disclosed |
| EP-1173445-A1 | ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS | Basell Technology Company B.V. (NL) | 2002-01-23 | — | — | EP | disclosed |
| WO-2001062764-A1 | ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-08-30 | — | — | WO | disclosed |
| US-6106599-A | Inks | XEROX CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| US-5672717-A | ANTITUMOR AGENTS TREATING CANCER | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5554764-A | DIPYRROMETHANES ARE CLAIMED. | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5464741-A | Palladium (II) octaethylporphine alpha-isothiocyanate as a phosphorescent label for immunoassays | HENWELL, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5446166-A | Reacting isocyanoacetate with prophosphatrane and acyl halide or acid anhydride | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5367084-A | Preparation of pyrrol and oxazole compounds: formation of porphyrins and c-acyl-α-amino acid esters therefrom | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276514-A1 | Tyrosine kinase inhibitors | ABL1, RET, ERBB2 | CYP1A2 2963/4885CYP2C9 2609/4885CYP2C19 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.