Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952197 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL7201249 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL8952275 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL8802655 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL8952345 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL8952266 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL9118291 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL9027308 | 0.88 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL8803812 | 0.87 | HSD17B10 (0.34) | MAPK10EPHX2MEN1KMT2AHTT | |
| SCHEMBL8803670 | 0.86 | TK1 (0.43) | MAPK10MEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623133-A4 | SUBSTITUTED AMINO ALKYL COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1995-10-11 | — | — | EP | disclosed |
| EP-0623133-A1 | SUBSTITUTED AMINO ALKYL COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1994011370-A1 | SUBSTITUTED AMINO ALKYL COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |