SCHEMBL9229529

SCHEMBL9229529

CCCCCCCCCC(=O)c1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
HPGD P15428 1/20 0.74
HSD17B3 P37058 7/20 0.67
HDAC1 Q13547 3/20 0.67
HDAC8 Q9BY41 3/20 0.67
MAPT P10636 2/20 0.63
LMNA P02545 2/20 0.63
TDP1 Q9NUW8 1/20 0.63
POLB P06746 1/20 0.61
FFAR1 O14842 1/20 0.61
CYP1A2 P05177 1/20 0.61
RAB9A P51151 1/20 0.61
HIF1A Q16665 1/20 0.61
HDAC3 O15379 2/20 0.58
HDAC4 P56524 2/20 0.58
HDAC7 Q8WUI4 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC10 Q969S8 2/20 0.58
HDAC11 Q96DB2 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10282853 1.00 L3MBTL1 (0.74) L3MBTL1SMN1; SMN2HPGDHSD17B3HDAC1
SCHEMBL13670588 1.00 L3MBTL1 (0.74) L3MBTL1SMN1; SMN2HPGDHSD17B3HDAC1
SCHEMBL4453789 0.98 L3MBTL1 (0.77) L3MBTL1SMN1; SMN2HPGDHSD17B3HDAC1
SCHEMBL6606979 0.93 L3MBTL1 (0.79) L3MBTL1SMN1; SMN2HPGDHSD17B3HDAC1
SCHEMBL9346532 0.90 HSD17B3 (0.67) L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT
SCHEMBL964590 0.89 L3MBTL1 (0.80) L3MBTL1HSD17B3HDAC1HDAC8MAPT
SCHEMBL5434100 0.89 L3MBTL1 (0.80) L3MBTL1HSD17B3HDAC1HDAC8MAPT
SCHEMBL1195162 0.89 L3MBTL1 (0.80) L3MBTL1HSD17B3HDAC1HDAC8MAPT
SCHEMBL2125312 0.89 L3MBTL1 (0.80) L3MBTL1HSD17B3HDAC1HDAC8MAPT
SCHEMBL967963 0.89 L3MBTL1 (0.80) L3MBTL1HSD17B3HDAC1HDAC8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382380-A Ferroelectric material for displays KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
EP-0360042-B1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU (JP) 1993-11-03 EP disclosed
EP-0360042-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed