SCHEMBL9229705

SCHEMBL9229705

COc1cccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
PDE4D Q08499 9/20 0.49
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
PDK2 Q15119 2/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
OPRK1 P41145 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
IDO1 P14902 1/20 0.40
KDM1A O60341 1/20 0.39
GAA P10253 1/20 0.39
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14191207 0.90 ESR1 (0.46) ESR1ESR2PDE4DABL1ABCB1
SCHEMBL14584274 0.90 ESR1 (0.45) ESR1ESR2PDE4DPDK2MEN1
SCHEMBL14191205 0.89 ESR1 (0.47) ESR1ESR2PDK2MEN1KMT2A
SCHEMBL17456246 0.87 ESR1 (0.49) ESR1ESR2PDE4DABL1ABCB1
SCHEMBL29462973 0.86 PDE4D (0.53) ESR1ESR2PDE4DABL1ABCB1
SCHEMBL649109 0.86 PDE4D (0.53) ESR1ESR2PDE4DABL1ABCB1
SCHEMBL18184909 0.86 PDE4D (0.47) ESR1PDE4DABL1ABCB1BCR
SCHEMBL15691555 0.85 ESR1 (0.57) ESR1ESR2PDE4DABL1ABCB1
SCHEMBL17445878 0.83 ESR1 (0.44) ESR1ESR2PDK2MEN1KMT2A
SCHEMBL18184919 0.82 ESR1 (0.43) ESR1ESR2PDE4DPDK2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5447960-A Fungicidal use of phenolic aromatic compounds DOWELANCO (US) 1995-09-05 US disclosed