SCHEMBL9230256

SCHEMBL9230256

C=C(C)C(=O)OC(C)N1C(C)(C)CCCC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11362648 0.77 TSHR (0.38) TSHRNFKB1CYP2C19
SCHEMBL2036449 0.72 KMT2A (0.43) TSHRALDH1A1
SCHEMBL2817068 0.72 TSHR (0.38) TSHRALDH1A1
SCHEMBL226077 0.72 ALDH1A1 (0.37) TSHRNFKB1CYP2C19ALDH1A1
SCHEMBL6570452 0.71 TSHR (0.41) TSHRALDH1A1
SCHEMBL3883739 0.71 TSHR (0.41) TSHRALDH1A1
SCHEMBL409640 0.70 TSHR (0.37) TSHRALDH1A1
SCHEMBL1054073 0.69 ALDH1A1 (0.34) TSHRNFKB1CYP2C19ALDH1A1
SCHEMBL28844537 0.68 TSHR (0.43) TSHRNFKB1CYP2C19
SCHEMBL7562327 0.67 TSHR (0.34) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476882-A Containing 2,2,6,6-tetraalkylpiperidine derivative CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
US-4511596-A 2,2,6,6-TETRAALKYLPIPERIDINE DERIVATIVES AS CURING PROMOTERS CIBA-GEIGY CORPORATION (US) 1985-04-16 US disclosed
US-4294949-A ACRYLATES OR ACRYLAMIDES WHICH CARRY N-HETEROCYCLIC RINGS CIBA-GEIGY CORPORATION (US) 1981-10-13 US disclosed
US-4276401-A N-Heterocyclic substituted acryloyl polymeric compounds CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4210612-A LIGHT STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
EP-0010518-A1 Acrylic copolymers bearing N-heterocyclic side rings, their use, and process for their preparation CIBA-GEIGY AG (CH) 1980-04-30 EP disclosed
EP-0001840-A2 Stabilising mixtures, process for stabilising synthetic materials against light with these mixtures and synthetic materials so stabilised CIBA-GEIGY AG (CH) 1979-05-16 EP disclosed
EP-0000496-A1 Acrylic polymers substituted by N-heterocyclic rings and their use as light protection agents CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed