Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401972 | 0.83 | MAPK1 (0.40) | MAPK1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL7764233 | 0.78 | MAPK1 (0.36) | MAPK1SMN1; SMN2 | |
| SCHEMBL9088562 | 0.78 | HSD17B10 (0.36) | MAPK1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL8019096 | 0.73 | HTT (0.42) | MAPK1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL829258 | 0.72 | ALDH1A1 (0.47) | MAPK1HSD17B10 | |
| SCHEMBL9485966 | 0.71 | MAPK1 (0.71) | MAPK1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL7764225 | 0.71 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL8056548 | 0.71 | ALDH1A1 (0.46) | MAPK1HSD17B10 | |
| SCHEMBL10831333 | 0.70 | MAPK1 (0.40) | MAPK1HSD17B10HTT | |
| SCHEMBL10831559 | 0.69 | ALDH1A1 (0.38) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0671401-A1 | Beta lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1995-09-13 | — | — | EP | disclosed |