Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | MARS1 | P56192 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446161 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9230518 | 0.89 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9222934 | 0.85 | HDAC6 (0.39) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL4968006 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8446252 | 0.75 | HDAC6 (0.42) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL9225003 | 0.74 | HDAC6 (0.41) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL7449974 | 0.71 | HDAC6 (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7954207 | 0.71 | HDAC6 (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8444883 | 0.70 | MEN1 (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL2943210 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654473-A1 | Cyclopropane derivatives and antiviral agents containing the same | Ajinomoto Co., Inc. (JP) | 1995-05-24 | — | — | EP | disclosed |