Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232640 | 0.81 | MAP3K14 (0.48) | APPBACE1 | |
| Hydrochloric Acid SCHEMBL9234205 | 0.81 | BACE1 (0.39) | APPBACE1CTNNB1WNT3AKCNH2 | |
| SCHEMBL9233832 | 0.81 | AKR1B1 (0.51) | APPBACE1CTNNB1 | |
| Hydrochloric Acid SCHEMBL9233886 | 0.76 | KMT2A (0.36) | KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9228764 | 0.75 | MAPT (0.41) | MEN1KMT2ACYP2C9CYP3A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9232618 | 0.75 | APP (0.38) | APPBACE1CYP3A4SMN1; SMN2 | |
| SCHEMBL9228772 | 0.73 | RYR2 (0.39) | CYP2C9TSHRCYP2C19CYP3A4KCNH2 | |
| SCHEMBL6580916 | 0.71 | RAB9A (0.43) | APPBACE1MEN1KMT2ATSHR | |
| SCHEMBL6578320 | 0.70 | SMN1; SMN2 (0.42) | APPBACE1MEN1KMT2ATSHR | |
| SCHEMBL8793923 | 0.70 | AKR1B1 (0.46) | BACE1MEN1KMT2ATSHRCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639557-A1 | TRIALKYLAMINE DERIVATIVE AND AMELIORANT FOR DIGESTIVE TRACT MOVEMENT CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5380748-A | Trialkylamine derivative and ameliorant for digestive tract movement containing the same | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |