Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230590 | 1.00 | SIGMAR1 (0.50) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9232557 | 0.90 | SIGMAR1 (0.59) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10365169 | 0.81 | SIGMAR1 (0.52) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4501237 | 0.81 | SIGMAR1 (0.52) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4501240 | 0.81 | SIGMAR1 (0.52) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL9005481 | 0.80 | SIGMAR1 (0.50) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL9005477 | 0.80 | SIGMAR1 (0.50) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL21425473 | 0.78 | SIGMAR1 (0.47) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL31104589 | 0.78 | SIGMAR1 (0.47) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22881858 | 0.74 | SIGMAR1 (0.43) | SIGMAR1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |