Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | GRN | P28799 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444839 | 0.89 | ALDH1A1 (0.58) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL4891798 | 0.89 | ALDH1A1 (0.58) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL561849 | 0.89 | ALDH1A1 (0.58) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| Hydrochloric Acid SCHEMBL4862500 | 0.88 | ALDH1A1 (0.57) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL3491590 | 0.87 | KDM4C (0.49) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL2327074 | 0.84 | ALDH1A1 (0.55) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL2326561 | 0.84 | ALDH1A1 (0.55) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL8742462 | 0.84 | GRN (0.71) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL2326554 | 0.84 | ALDH1A1 (0.55) | KDM4CALDH1A1GAAMAPTHDAC8 | |
| SCHEMBL6654999 | 0.83 | ALDH1A1 (0.54) | KDM4CALDH1A1GAAMAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652009-A1 | Identification and use of protease inhibitors | ELI LILLY AND COMPANY (US) | 1995-05-10 | — | — | EP | disclosed |