Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189401 | 0.86 | TSHR (0.57) | TSHRNR3C1CRHBPCRHR2PTPN1 | |
| SCHEMBL5983797 | 0.81 | TDP1 (0.42) | TSHRALDH1A1NPSR1NPC1GLA | |
| SCHEMBL156664 | 0.80 | MEN1 (0.56) | RECQLALDH1A1HDAC8HDAC6SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27486735 | 0.79 | MEN1 (0.54) | RECQLALDH1A1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL1252387 | 0.79 | MEN1 (0.54) | RECQLALDH1A1HDAC8HDAC6 | |
| SCHEMBL11794847 | 0.76 | TSHR (0.53) | TSHRNR3C1CRHBPCRHR2PTPN1 | |
| Hydrochloric Acid SCHEMBL27715118 | 0.76 | GAA (0.51) | TSHRALDH1A1CYP2C19HDAC6HTT | |
| SCHEMBL28565303 | 0.75 | CYP2C19 (0.71) | TSHRNR3C1CRHBPCRHR2CNR2 | |
| SCHEMBL10906279 | 0.75 | NR3C1 (0.49) | TSHRNR3C1PTPN1CNR2CYP2C19 | |
| SCHEMBL264790 | 0.75 | PTPN1 (0.52) | TSHRNR3C1CRHBPCRHR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672669-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1995-09-20 | — | — | EP | disclosed |