Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MARS1 | P56192 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227950 | 0.92 | NPSR1 (0.51) | NPSR1KDM4EMAPTMAPK1RECQL | |
| SCHEMBL9228112 | 0.89 | NPSR1 (0.58) | NPSR1KDM4EMAPTMAPK1GAA | |
| SCHEMBL9279562 | 0.85 | NPSR1 (0.72) | NPSR1KDM4EMAPTMAPK1GAA | |
| SCHEMBL9229776 | 0.85 | NPSR1 (0.58) | NPSR1KDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL25479257 | 0.83 | NPSR1 (0.49) | NPSR1KDM4EMAPTMAPK1RECQL | |
| SCHEMBL9225263 | 0.79 | NPSR1 (0.52) | NPSR1KDM4EMAPTMAPK1GAA | |
| SCHEMBL9229584 | 0.78 | NPSR1 (0.48) | NPSR1KDM4EGAAALDH1A1CYP1A2 | |
| SCHEMBL25174337 | 0.78 | KDM4E (0.46) | NPSR1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL25479341 | 0.78 | KDM4E (0.46) | NPSR1KDM4EMAPTMAPK1GAA | |
| SCHEMBL25479342 | 0.78 | KDM4E (0.47) | NPSR1KDM4EMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | claimed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | disclosed |