Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 10/20 | 0.68 |
| ▸ | GSK3A | P49840 | 2/20 | 0.62 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 3/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398120 | 0.86 | HINT1 (0.70) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL9236777 | 0.86 | HINT1 (0.67) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL186043 | 0.85 | HINT1 (0.69) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL1034011 | 0.85 | HINT1 (0.69) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL442292 | 0.85 | HINT1 (0.67) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL30396629 | 0.85 | HINT1 (0.66) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL1533274 | 0.83 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL9231860 | 0.83 | HINT1 (0.71) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL5219707 | 0.82 | GSK3A (0.80) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL1904550 | 0.82 | TYMP (0.76) | HINT1GSK3ARPS6KA3MAPK14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653438-A2 | Oligonucleotide compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |