Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.44 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466162 | 0.89 | MEN1 (0.65) | MAPTMEN1KMT2AHPGDHTT | |
| Ammonia Solution, Strong SCHEMBL28461881 | 0.88 | MEN1 (0.63) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL12347503 | 0.84 | MEN1 (0.59) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL9233195 | 0.80 | KMT2A (0.60) | MAPTMEN1KMT2AHPGDLMNA | |
| SCHEMBL3328543 | 0.80 | MAPT (0.79) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL4163474 | 0.80 | MAPT (0.79) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL11806188 | 0.79 | MEN1 (0.72) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL9232889 | 0.79 | MEN1 (0.54) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL8934649 | 0.78 | MAPT (0.76) | MAPTMEN1KMT2AHPGDHTT | |
| Fluoride SCHEMBL29135589 | 0.78 | MAPT (0.76) | MAPTMEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |