Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328543 | 1.00 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8934655 | 0.97 | MAPT (0.76) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Fluoride SCHEMBL29135589 | 0.97 | MAPT (0.76) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8934649 | 0.97 | MAPT (0.76) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL5140929 | 0.93 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL2818369 | 0.93 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL268150 | 0.91 | MEN1 (0.68) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL6198840 | 0.89 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11302349 | 0.89 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1713212 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105829-A | Chlorination method of p-nitrophenyl methyl sulfide | 江苏永创医药科技股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117105830-A | Fluorination method of p-nitrophenyl methyl sulfide | 江苏永创医药科技股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-110702858-A | Method for testing deodorization effect of super absorbent resin | 宜兴丹森科技有限公司 | 2020-01-17 | — | — | CN | claimed |
| EP-0019712-A1 | Process for partial reduction of polynitrodiaryl compounds | BAYER AG (DE) | 1980-12-10 | — | — | EP | claimed |
| JP-57126982-A | — | — | None | — | — | JP | disclosed |
| CN-115354350-B | Method for in-situ nitration of electrocatalytic halogenated aromatic hydrocarbon | 平顶山学院 | 2025-02-25 | — | — | CN | disclosed |
| CN-118724774-A | N-O bond guanidine compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2024-10-01 | — | — | CN | disclosed |
| US-20240165259-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| CN-117899873-A | Transition metal catalyst and preparation method and application thereof | 厦门大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-114478150-B | S-deuterated methyl-aryl sulfonyl thioester compound and synthetic method and application thereof | 浙江工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-113999149-B | Preparation method for synthesizing diaryl sulfide compound based on L-cysteine | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-114163366-B | Preparation method of 4,4' -diamino diphenyl sulfone | 河北建新化工股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-4170708-A | FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-10-09 | — | — | US | disclosed |
| EP-0000563-A1 | Process for preparing aromatic urethanes | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-02-07 | — | — | EP | disclosed |
| US-4134880-A | Process for producing an aromatic urethane from nitro compounds, hydroxyl compounds and carbon monoxide using metal-Lewis acid-ammonia catalyst systems | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4080365-A | Process for preparing aromatic urethanes | MITSUI TOATSU CHEMICALS (JA) | 1978-03-21 | — | — | US | disclosed |
| US-4070391-A | Process for producing isocyanate from nitro compounds and carbon monoxide using rhodium oxide catalysts | ETHYL CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4052437-A | PROCESS FOR PRODUCING URETHANE FROM NITRO COMPOUNDS, HYDROXYL COMPOUNDS AND CARBON MONOXIDE USING RHODIUM OXIDE CATALYSTS | ETHYL CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4005150-A | Phenyl ethers having juvenile hormone activity | CESKOSLOVENSKA AKADEMIE VED (CS) | 1977-01-25 | — | — | US | disclosed |
| US-3976769-A | INSECTICIDE | AIRWICK INDUSTRIES, INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240165259-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | CILK1, SYMPK, DCK | MAPT 3211/4885MEN1 1370/4885KMT2A 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.