Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971739 | 0.87 | OPRM1 (0.57) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL5242605 | 0.84 | OPRM1 (0.60) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL9231201 | 0.83 | CYP2D6 (0.48) | OPRM1SMN1; SMN2CYP3A4SIGMAR1ALDH1A1 | |
| SCHEMBL22770550 | 0.83 | OPRM1 (0.53) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL17140513 | 0.83 | OPRM1 (0.53) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL7839246 | 0.82 | SMN1; SMN2 (0.46) | OPRM1SMN1; SMN2SIGMAR1ALDH1A1TSHR | |
| SCHEMBL2985757 | 0.82 | SMN1; SMN2 (0.75) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL12581100 | 0.81 | OPRM1 (0.51) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL15461526 | 0.81 | CYP2D6 (0.59) | OPRM1SMN1; SMN2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL9954167 | 0.81 | CYP1A2 (0.43) | OPRM1SMN1; SMN2CYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |