Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233629 | 1.00 | ALOX5 (0.50) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9234952 | 1.00 | ALOX5 (0.50) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9233624 | 1.00 | ALOX5 (0.50) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9234938 | 1.00 | ALOX5 (0.50) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9233636 | 1.00 | ALOX5 (0.50) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9089186 | 0.82 | ALOX5 (0.57) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9089183 | 0.82 | ALOX5 (0.57) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9090758 | 0.82 | ALOX5 (0.57) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9089189 | 0.82 | ALOX5 (0.57) | ALOX5EPHX2MEN1KMT2AMAPT | |
| SCHEMBL9090751 | 0.82 | ALOX5 (0.57) | ALOX5EPHX2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506261-A | Substituted aryl- and heteroarylalkenyl-N-hydroxyurea inhibitors of leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1996-04-09 | — | — | US | disclosed |