Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 8/20 | 0.36 |
| ▸ | TOP2A | P11388 | 7/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216986 | 0.87 | MEN1 (0.46) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL9233707 | 0.84 | TOP2A (0.37) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL6216507 | 0.83 | TOP2A (0.39) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL6213897 | 0.82 | GSK3B (0.49) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL9047018 | 0.82 | TOP2A (0.42) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL8131150 | 0.82 | MEN1 (0.39) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL7524708 | 0.80 | TOP2A (0.44) | GSK3BTOP2ATOP2BPOLBKCNH2 | |
| SCHEMBL8327191 | 0.80 | MEN1 (0.37) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL9416465 | 0.79 | TOP2A (0.42) | MEN1KMT2AGSK3BTOP2ATOP2B | |
| SCHEMBL10377463 | 0.76 | TOP2A (0.40) | MEN1KMT2AGSK3BTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | claimed |