Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 2/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533545 | 0.86 | MPO (0.48) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4966454 | 0.85 | PNP (0.45) | PNPTLR7PDE4APDE4BPDE4C | |
| SCHEMBL1262618 | 0.85 | PNP (0.45) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3308556 | 0.85 | PNP (0.45) | PNPTLR7P2RX3PDE4APDE4B | |
| SCHEMBL3310264 | 0.84 | PNP (0.44) | PNPTLR7PDE4APDE4BPDE4C | |
| SCHEMBL3021036 | 0.84 | PNP (0.44) | PNPTLR7PDE4APDE4BPDE4C | |
| SCHEMBL3303803 | 0.84 | PNP (0.44) | PNPTLR7PDE4APDE4BPDE4C | |
| SCHEMBL18247 | 0.84 | PNP (0.59) | PNPPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL17186467 | 0.83 | PNP (0.43) | PNPTLR7PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL17186488 | 0.83 | PNP (0.43) | PNPTLR7PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7267956-A | — | — | None | — | — | JP | disclosed |
| JP-H07267956-A | BENZYLGUANINE DERIVATIVE | TOAGOSEI CO LTD | 1995-10-17 | — | — | JP | disclosed |