Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | MTOR | P42345 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.79 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235257 | 1.00 | LTB4R (0.79) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL10511272 | 0.88 | LTB4R (1.00) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL29462291 | 0.88 | LTB4R (1.00) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL1894359 | 0.88 | LTB4R (1.00) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL10511276 | 0.88 | LTB4R (1.00) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL9237815 | 0.88 | LTB4R (1.00) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL8891725 | 0.87 | LTB4R (0.66) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL8772137 | 0.87 | LTB4R (0.66) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL8891730 | 0.87 | LTB4R (0.66) | LTB4RALDH1A1MAPTMTORPMP22 | |
| SCHEMBL9235266 | 0.84 | LTB4R (0.66) | LTB4RALDH1A1MAPTMTORPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339046-B1 | LEUKOTRIENE B 4 ANALOGS | UPJOHN CO (US) | 1995-02-15 | — | — | EP | claimed |
| EP-0339046-A1 | LEUKOTRIENE B 4? ANALOGS. | UPJOHN CO (US) | 1989-11-02 | — | — | EP | claimed |
| WO-1988005045-A1 | LEUKOTRIENE B4 ANALOGS | THE UPJOHN COMPANY (US) | 1988-07-14 | — | — | WO | claimed |