Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233223 | 0.99 | FAAH (0.49) | FAAHPTGER2TRPA1HDAC1ADRB2 | |
| SCHEMBL10649974 | 0.92 | PTGER2 (0.48) | FAAHPTGER2ADRB2ADRB1ADRB3 | |
| SCHEMBL8894974 | 0.89 | ADRB3 (0.49) | HDAC1ADRB2ADRB1ADRB3PPARG | |
| SCHEMBL9231232 | 0.88 | ADRB3 (0.47) | HDAC1ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL9231881 | 0.87 | HDAC1 (0.60) | HDAC1ALDH1A1MAPTRXFP1 | |
| SCHEMBL10650968 | 0.87 | PTGER2 (0.63) | FAAHPTGER2PPARG | |
| SCHEMBL9453938 | 0.87 | PTGER2 (0.63) | FAAHPTGER2PPARG | |
| SCHEMBL10651370 | 0.87 | PTGER2 (0.63) | FAAHPTGER2PPARG | |
| SCHEMBL8421753 | 0.87 | PTGER2 (0.47) | FAAHPTGER2ADRB2ADRB1PPARG | |
| SCHEMBL11375764 | 0.83 | PPARG (0.54) | PTGER2ADRB3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |