Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548463 | 0.92 | THRA (0.55) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9233039 | 0.92 | THRA (0.50) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7290713 | 0.90 | CYP24A1 (0.53) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL972021 | 0.90 | CYP24A1 (0.53) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9233137 | 0.88 | MAPT (0.50) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5665208 | 0.88 | MAOB (0.52) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20572886 | 0.86 | MAOB (0.54) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8050780 | 0.85 | MEN1 (0.55) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19900425 | 0.84 | MEN1 (0.53) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2064320 | 0.84 | MEN1 (0.53) | MAPTKMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641792-A1 | 1,2-Dithiole derivatives and therapeutic agents containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-03-08 | — | — | EP | disclosed |