Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.44 |
| ▸ | TACR1 | P25103 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234523 | 1.00 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| SCHEMBL8836563 | 1.00 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| SCHEMBL9235668 | 1.00 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| SCHEMBL9234532 | 1.00 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8477164 | 0.99 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL9239046 | 0.99 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL9239058 | 0.99 | NAMPT (0.44) | NAMPTTACR1MAPK1FNTAFNTB | |
| SCHEMBL8836941 | 0.91 | TACR1 (0.47) | TACR1 | |
| SCHEMBL9234549 | 0.91 | TACR1 (0.47) | TACR1 | |
| SCHEMBL9234555 | 0.91 | TACR1 (0.47) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |