Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.41 |
| ▸ | CA2 | P00918 | 10/20 | 0.41 |
| ▸ | CA4 | P22748 | 10/20 | 0.41 |
| ▸ | CA9 | Q16790 | 10/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234549 | 1.00 | TACR1 (0.47) | TACR1ABCB1CA1CA2CA4 | |
| SCHEMBL9234555 | 1.00 | TACR1 (0.47) | TACR1ABCB1CA1CA2CA4 | |
| SCHEMBL8480611 | 1.00 | TACR1 (0.47) | TACR1ABCB1CA1CA2CA4 | |
| SCHEMBL8477810 | 0.94 | GPR183 (0.45) | TACR1GPR183 | |
| SCHEMBL9239267 | 0.94 | GPR183 (0.45) | TACR1GPR183 | |
| SCHEMBL9239257 | 0.94 | GPR183 (0.45) | TACR1GPR183 | |
| SCHEMBL9236774 | 0.93 | L3MBTL1 (0.42) | TACR1GPR183 | |
| SCHEMBL8478659 | 0.93 | L3MBTL1 (0.42) | TACR1GPR183 | |
| SCHEMBL8478660 | 0.93 | L3MBTL1 (0.42) | TACR1GPR183 | |
| SCHEMBL9236781 | 0.93 | L3MBTL1 (0.42) | TACR1GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670505-A | TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |