Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238978 | 0.98 | MTNR1A (0.47) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL9239494 | 0.95 | MTNR1A (0.47) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL10339701 | 0.86 | MTNR1A (0.50) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL3298869 | 0.84 | MTNR1A (0.49) | MTNR1AHTR1AKMT2AALDH1A1MCHR1 | |
| SCHEMBL25335293 | 0.84 | HTR1B (0.46) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL5871763 | 0.84 | MTNR1A (0.46) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL13534270 | 0.84 | MTNR1A (0.50) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL25334638 | 0.83 | HTR1B (0.45) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL8584312 | 0.82 | MTNR1A (0.60) | MTNR1AHTR1ASLC6A4 | |
| SCHEMBL4309152 | 0.82 | MTNR1A (0.48) | MTNR1AHTR1AKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652217-A1 | N-substituted imidazole derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-05-10 | — | — | EP | disclosed |