Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836811 | 1.00 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CTACR1NAMPT | |
| SCHEMBL8836478 | 0.96 | SMN1; SMN2 (0.44) | ADRA2AADRA2BADRA2CTACR1NAMPT | |
| SCHEMBL7830364 | 0.96 | SMN1; SMN2 (0.44) | ADRA2AADRA2BADRA2CTACR1NAMPT | |
| Hydrochloric Acid SCHEMBL7560436 | 0.87 | TACR1 (0.42) | TACR1 | |
| Hydrochloric Acid SCHEMBL8476084 | 0.86 | TACR1 (0.44) | TACR1 | |
| Hydrochloric Acid SCHEMBL9233950 | 0.86 | TACR1 (0.44) | TACR1 | |
| Hydrochloric Acid SCHEMBL9241357 | 0.85 | TACR1 (0.48) | TACR1 | |
| Hydrochloric Acid SCHEMBL7556699 | 0.85 | TACR1 (0.42) | TACR1 | |
| Hydrochloric Acid SCHEMBL7560528 | 0.85 | TACR1 (0.41) | TACR1 | |
| Hydrochloric Acid SCHEMBL8480146 | 0.84 | TACR1 (0.43) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |