Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 5/20 | 0.40 |
| ▸ | NMT2 | O60551 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235669 | 1.00 | KMT2A (0.53) | KMT2APOLBSLC6A5NMT1NMT2 | |
| SCHEMBL9088322 | 1.00 | KMT2A (0.53) | KMT2APOLBSLC6A5NMT1NMT2 | |
| SCHEMBL20450608 | 0.94 | SLC6A5 (0.47) | KMT2APOLBSLC6A5NMT1NMT2 | |
| SCHEMBL20450607 | 0.94 | SLC6A5 (0.47) | KMT2APOLBSLC6A5NMT1NMT2 | |
| SCHEMBL20341486 | 0.90 | KMT2A (0.46) | KMT2APOLBSLC6A5NMT1NMT2 | |
| SCHEMBL20263699 | 0.89 | KMT2A (0.46) | KMT2APOLBL3MBTL1NOD1 | |
| SCHEMBL21523354 | 0.89 | KMT2A (0.46) | KMT2APOLBL3MBTL1NOD1 | |
| SCHEMBL20263696 | 0.89 | KMT2A (0.46) | KMT2APOLBL3MBTL1NOD1 | |
| SCHEMBL22247624 | 0.88 | KMT2A (0.43) | KMT2APOLBSLC6A5NMT1NMT2 | |
| SCHEMBL22228935 | 0.88 | KMT2A (0.43) | KMT2APOLBSLC6A5NMT1NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641776-A2 | Thioglycerol derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |