Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933979 | 0.82 | GBA1 (0.44) | MAOBCYP19A1TAAR1 | |
| SCHEMBL30431712 | 0.76 | TAAR1 (0.48) | MAOBKMT2ATAAR1MBTD1L3MBTL3 | |
| SCHEMBL24187547 | 0.76 | TAAR1 (0.48) | MAOBKMT2ATAAR1MBTD1L3MBTL3 | |
| SCHEMBL16334340 | 0.73 | SMN1; SMN2 (0.47) | MAOBKMT2ATAAR1MBTD1L3MBTL3 | |
| SCHEMBL16334058 | 0.73 | SMN1; SMN2 (0.47) | MAOBMAOAKMT2ATAAR1MBTD1 | |
| SCHEMBL28496876 | 0.72 | CA1 (0.43) | MAOBCYP19A1KMT2A | |
| SCHEMBL5855626 | 0.70 | TAAR1 (0.40) | MAOBTAAR1IDO1AGXTSMN1; SMN2 | |
| SCHEMBL31494618 | 0.70 | HTR1D (0.46) | MAOBMAOAKMT2ATAAR1 | |
| SCHEMBL18367810 | 0.69 | PTGS2 (0.49) | KMT2AMBTD1L3MBTL3PARP1SMN1; SMN2 | |
| SCHEMBL26187523 | 0.68 | TAAR1 (0.44) | MAOBTAAR1MBTD1L3MBTL3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339046-B1 | LEUKOTRIENE B 4 ANALOGS | UPJOHN CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5116981-A | Antiinflammatory leukotriene B4 analogs | THE UPJOHN COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0339046-A1 | LEUKOTRIENE B 4? ANALOGS. | UPJOHN CO (US) | 1989-11-02 | — | — | EP | disclosed |
| WO-1988005045-A1 | LEUKOTRIENE B4 ANALOGS | THE UPJOHN COMPANY (US) | 1988-07-14 | — | — | WO | disclosed |