Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236828 | 1.00 | PPARG (0.43) | PPARGPPARAL3MBTL1FFAR1SLC1A3 | |
| SCHEMBL9241984 | 0.88 | PPARG (0.47) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9241640 | 0.85 | KMT2A (0.44) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9241636 | 0.85 | KMT2A (0.44) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9238609 | 0.85 | KMT2A (0.47) | L3MBTL1FFAR1KMT2AMEN1CYP2D6 | |
| SCHEMBL9238607 | 0.85 | KMT2A (0.47) | L3MBTL1FFAR1KMT2AMEN1CYP2D6 | |
| SCHEMBL9237130 | 0.83 | CYP1A2 (0.51) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9238852 | 0.83 | PPARG (0.50) | PPARGPPARAFFAR1KMT2APARP10 | |
| SCHEMBL9237136 | 0.83 | CYP1A2 (0.51) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9238843 | 0.83 | PPARG (0.50) | PPARGPPARAFFAR1KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108240-A | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 1995-09-13 | — | — | CN | claimed |
| EP-0658539-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1995-06-21 | — | — | EP | claimed |
| JP-7267908-A | — | — | None | — | — | JP | disclosed |
| JP-H07267908-A | EXCITATORY AMINO ACID RECEPTOR ANTAGONIST | ELI LILLY & CO | 1995-10-17 | — | — | JP | disclosed |
| CN-1108240-A | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 1995-09-13 | — | — | CN | disclosed |
| EP-0658539-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |