Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SRSF6 | Q13247 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9236201 | 0.99 | ADRB2 (0.38) | ADRB2NFKB1NFKB2RELAKDM4E | |
| Hydrochloric Acid SCHEMBL9232047 | 0.99 | ADRB2 (0.38) | ADRB2NFKB1NFKB2RELAKDM4E | |
| SCHEMBL9097387 | 0.86 | ADRB2 (0.41) | ADRB2KDM4EALDH1A1ADRB1SLC6A2 | |
| Hydrochloric Acid SCHEMBL9236348 | 0.85 | ADRB2 (0.37) | ADRB2NFKB1NFKB2RELAKDM4E | |
| SCHEMBL9095407 | 0.84 | ADRB2 (0.36) | ADRB2KDM4EALDH1A1EZH2ADRB1 | |
| SCHEMBL9096487 | 0.84 | ADRB2 (0.36) | ADRB2NFKB1NFKB2RELAKDM4E | |
| Hydrochloric Acid SCHEMBL9095026 | 0.84 | ADRB2 (0.37) | ADRB2KDM4EALDH1A1ADRB1SLC6A2 | |
| SCHEMBL9095909 | 0.83 | ADRB2 (0.38) | ADRB2NFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL9095073 | 0.83 | CYP1A2 (0.37) | ADRB2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9094427 | 0.83 | ADRB2 (0.36) | ADRB2KDM4EALDH1A1EZH2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |