Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | GALR3 | O60755 | 1/20 | 0.76 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.76 |
| ▸ | GPR183 | P32249 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.76 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237624 | 0.87 | MEN1 (0.76) | MEN1NPC1GALR3NR2F2GPR183 | |
| Pyridaben SCHEMBL8372466 | 0.86 | MEN1 (1.00) | MEN1NPC1GALR3NR2F2GPR183 | |
| Pyridaben SCHEMBL27429 | 0.86 | MEN1 (1.00) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9775232 | 0.86 | MEN1 (0.74) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9239780 | 0.86 | MEN1 (0.74) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL4958414 | 0.86 | MEN1 (0.74) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9238710 | 0.85 | RAB9A (0.57) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL10371714 | 0.85 | MEN1 (0.56) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL3848520 | 0.85 | MEN1 (0.72) | MEN1NPC1GALR3NR2F2GPR183 | |
| SCHEMBL9235418 | 0.85 | MEN1 (0.72) | MEN1NPC1GALR3NR2F2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3385253-B1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING INC (US) | 2021-04-07 | — | — | EP | disclosed |
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0183212-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |
| US-4874861-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| EP-0183212-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-06-04 | — | — | EP | disclosed |