Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | GALR3 | O60755 | 1/20 | 0.66 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.66 |
| ▸ | GPR183 | P32249 | 1/20 | 0.66 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234574 | 0.89 | RAB9A (0.77) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9775230 | 0.87 | MEN1 (0.71) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9240320 | 0.86 | SMN1; SMN2 (0.51) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9830508 | 0.85 | MEN1 (0.69) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9775144 | 0.85 | RAB9A (0.69) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9238805 | 0.85 | MEN1 (0.74) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9828077 | 0.84 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9775209 | 0.83 | MEN1 (0.66) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9775159 | 0.83 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2AGALR3 | |
| SCHEMBL9775171 | 0.82 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |