Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701435 | 1.00 | PTGS2 (0.47) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL23174999 | 1.00 | PTGS2 (0.47) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL28375837 | 1.00 | PTGS2 (0.47) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL2671226 | 0.99 | PTGS2 (0.45) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL583151 | 0.94 | PTGS2 (0.41) | PTGS2TLR8KCNH2HSP90AA1HSP90AB1 | |
| SCHEMBL30305194 | 0.94 | PTGS2 (0.41) | PTGS2TLR8KCNH2HSP90AA1HSP90AB1 | |
| SCHEMBL29437643 | 0.83 | PTGS2 (0.44) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL28359937 | 0.83 | PTGS2 (0.44) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL29494843 | 0.83 | PTGS2 (0.44) | PTGS2TLR8KCNH2LIPGHSP90AA1 | |
| SCHEMBL28299064 | 0.83 | MEN1 (0.47) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300424-A1 | Vulcanization accelerators | THE B.F. GOODRICH COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0109955-B1 | RUBBER/METAL COMPOSITES | MONSANTO EUROPE S.A./N.V. (BE) | 1988-01-20 | — | — | EP | claimed |
| CN-108473766-A | Polyarylene sulfide resin composition and molded article | SK化学株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-108463485-A | polyarylene sulfide resin and preparation method thereof | SK化学株式会社 | 2018-08-28 | — | — | CN | disclosed |
| WO-2014012979-A2 | LATEX COMPOSITION | SOBELTEC (BE) | 2014-01-23 | — | — | WO | disclosed |
| WO-1995016738-A1 | ELECTRONEGATIVE-SUBSTITUTED BISMALEIMIDE ANTI-REVERSION COAGENTS | AKZO NOBEL N.V. (NL) | 1995-06-22 | — | — | WO | disclosed |
| EP-0389144-A2 | Ethylene-olefin rubbery copolymers and composition thereof for use as sponge rubber | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0300424-A1 | Vulcanization accelerators | THE B.F. GOODRICH COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0300424-A1 | Vulcanization accelerators | THE B.F. GOODRICH COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0109955-B1 | RUBBER/METAL COMPOSITES | MONSANTO EUROPE S.A./N.V. (BE) | 1988-01-20 | — | — | EP | disclosed |
| EP-0109955-A2 | Rubber/metal composites | MONSANTO EUROPE S.A./N.V. (BE) | 1984-05-30 | — | — | EP | disclosed |