Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237738 | 0.82 | KDM1A (0.42) | HTR2AHTR2CHTR2BKDM1AKDM4E | |
| SCHEMBL9237183 | 0.81 | DPP4 (0.36) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL9238233 | 0.76 | HTR2A (0.41) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL16372470 | 0.74 | HTR2A (0.53) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL22437509 | 0.74 | HTR2A (0.53) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL29457652 | 0.74 | HTR2A (0.53) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL29023696 | 0.74 | HTR2A (0.53) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL16211980 | 0.74 | HTR2A (0.53) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL29023699 | 0.74 | HTR2A (0.53) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL22855046 | 0.74 | HTR2A (0.61) | DPP4HTR2AHTR2CHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657455-A1 | Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them | EGIS GYOGYSZERGYAR (HU) | 1995-06-14 | — | — | EP | disclosed |