Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237968 | 0.83 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL9237172 | 0.81 | DPP4 (0.45) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL9236818 | 0.79 | HTR2A (0.40) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL9242476 | 0.78 | KMT2A (0.39) | MEN1KMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL8795487 | 0.75 | CHRNB2 (0.38) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8977341 | 0.75 | CHRNB2 (0.38) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9240648 | 0.74 | PTGS2 (0.34) | TSHRCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL3750791 | 0.70 | DPP4 (0.34) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL3750793 | 0.70 | DPP4 (0.34) | DPP4HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL3750797 | 0.70 | DPP4 (0.34) | DPP4HTR2AHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657455-A1 | Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them | EGIS GYOGYSZERGYAR (HU) | 1995-06-14 | — | — | EP | disclosed |