Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCND2 | P30279 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850735 | 0.82 | CNR2 (0.50) | KDM4EPARP1CDK4CCND1CCND2 | |
| SCHEMBL16293428 | 0.77 | ATM (0.45) | KDM4ENTRK1NTRK3L3MBTL1SLC22A12 | |
| SCHEMBL4142227 | 0.76 | PARP1 (0.37) | KDM4EALDH1A1HPGDPARP1NTRK1 | |
| SCHEMBL3777821 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1HPGDAPEX1GLA | |
| SCHEMBL4132770 | 0.75 | CDK4 (0.39) | PARP1CDK4CCND1CCND2CCND3 | |
| SCHEMBL13368743 | 0.75 | MEN1 (0.43) | KDM4EALDH1A1HPGDNTRK1NTRK3 | |
| SCHEMBL15334954 | 0.75 | CNR1 (0.48) | PARP1NTRK1NTRK3 | |
| SCHEMBL114693 | 0.74 | MTNR1A (0.57) | PARP1ENPP1MTNR1ASLC22A12KMT2A | |
| SCHEMBL4508432 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1HPGDPARP1NTRK1 | |
| SCHEMBL13343303 | 0.74 | ATM (0.65) | KDM4EALDH1A1HPGDNTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |