Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 16/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572237 | 0.92 | HIF1A (0.42) | HIF1ACHRNA7KDM4EPKM | |
| SCHEMBL496412 | 0.80 | HCRTR1 (0.43) | HIF1ACHRNA7KDM4EPKM | |
| SCHEMBL2446757 | 0.80 | HCRTR1 (0.43) | HIF1ACHRNA7KDM4EPKM | |
| SCHEMBL925561 | 0.76 | HCRTR1 (0.50) | — | |
| SCHEMBL924409 | 0.75 | KMT2A (0.45) | KDM4EPKM | |
| SCHEMBL924082 | 0.75 | HCRTR1 (0.42) | HIF1ACHRNA7 | |
| SCHEMBL496419 | 0.74 | HIF1A (0.38) | HIF1ACHRNA7KDM4EPKM | |
| SCHEMBL1572179 | 0.74 | RAB9A (0.43) | CHRNA7KDM4EPKM | |
| SCHEMBL923764 | 0.73 | HCRTR1 (0.49) | HIF1A | |
| SCHEMBL924556 | 0.73 | HCRTR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288429-B2 | 2-aza-bicyclo[3.3.0]octane derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-10-16 | — | — | US | disclosed |
| US-20110009461-A1 | 2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009461-A1 | 2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES | HCRTR2, HCRTR1, NPY2R | HIF1A 489/4885CHRNA7 152/4885KDM4E 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.