Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743553 | 0.86 | KDM4E (0.50) | KDM4EPOLBTSHRPTPN2PTPN1 | |
| SCHEMBL30782112 | 0.83 | KDM4E (0.47) | KDM4EPOLBTSHRPTPN2PTPN1 | |
| SCHEMBL9565497 | 0.81 | KDM4E (0.62) | KDM4EPOLBTSHRCA1CES1 | |
| SCHEMBL9241218 | 0.81 | KDM4E (0.53) | KDM4EPOLBTSHRCA1CHRM3 | |
| SCHEMBL8352025 | 0.81 | KDM4E (0.53) | KDM4EPOLBTSHRCA1CHRM3 | |
| SCHEMBL28776126 | 0.81 | TSHR (0.56) | KDM4EPOLBTSHRPTPN2PTPN1 | |
| SCHEMBL21068792 | 0.81 | TSHR (0.47) | KDM4EPOLBTSHRPTPN2PTPN1 | |
| SCHEMBL9241304 | 0.80 | KDM4E (0.51) | KDM4EPOLBTSHRCA1CHRM3 | |
| SCHEMBL21068743 | 0.79 | TSHR (0.45) | KDM4EPOLBTSHRPTPN2PTPN1 | |
| SCHEMBL9233739 | 0.79 | KDM4E (0.50) | KDM4EPOLBTSHRCA1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995022330-A1 | ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-08-24 | — | — | WO | disclosed |