Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233810 | 0.93 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL18672266 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL16901922 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL9237673 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL15596807 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL15567329 | 0.89 | MAPK14 (0.47) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL9240320 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL16901927 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL9239275 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHPGDHTTATM | |
| SCHEMBL10927755 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHPGDHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0088384-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDAL, INSECTICIDAL, ACARICIDAL, NEMATICIDAL COMPOSITIONS CONTAINING SAID DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4571397-A | Pyridazinone derivatives, preparation thereof, and agricultural and horticultural fungicidal, insecticidal, acaricidal, nematicidal compositions containing said derivatives | NISSAN CHEMICAL INDUSTRIES (JP) | 1986-02-18 | — | — | US | disclosed |